РАЗРАБОТКА ТЕХНОЛОГИИ ОЧИСТКИ РЕКОМБИНАНТНОГО СЛИТОГО ПОЛИПЕПТИДА ИЗ КАПСИДНЫХ БЕЛКОВ ВИРУСА ДЕНГЕ
https://doi.org/10.20914/2304-4691-2025-2-30-32
About the Authors
В. ЛемешеваRussian Federation
Д. Поляков
Russian Federation
Н. Савельев
Russian Federation
Ю. Плетюхина
Russian Federation
С. Рабдано
Russian Federation
References
1. Byk L.A., Gamarnik A.V. Properties and functions of the dengue virus capsid protein // Annual Review of Virology. 2016. Vol. 3. № 1. P. 263-281.
2. Jonsson C.B., Gallegos J., Fero P. et al. Purification and characterization of the Sin Nombre virus nucleocapsid protein expressed in Escherichia coli // Protein Expression and Purification. 2001. Vol. 23. № 1. P. 134-141.
3. Gil L., Cobas K., Lazo L. et al. A tetravalent formulation based on recombinant nucleocapsid-like particles from dengue viruses induces a functional immune response in mice and monkeys // Journal of Immunology. 2016. Vol. 197. № 9. P. 3597-3606.
4. Brudenell E.L., Pohare M.B., Zafred D. et al. Efficient overexpression and purification of severe acute respiratory syndrome coronavirus 2 nucleocapsid proteins in Escherichia coli // Biochemical Journal. 2024. Vol. 481. № 11. P. 669-682.
5. Chen C., Zhang Z., Zheng Q. et al. Purification and inhibitor screening of the full-length SARS-CoV-2 nucleocapsid protein // Journal of Immunology. 2025. Vol. 202. № 1. P. 1-10. doi: 10.4049/jimmunol.1600927
Review
For citations:
, , , , . Topical biotechnology. 2025;(2):30-32. (In Russ.) https://doi.org/10.20914/2304-4691-2025-2-30-32
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