actbiotechАктуальная биотехнологияTopical biotechnology2304-4691ВГУИТ10.20914/2304-4691-2025-2-30-32actbiotech-5491Research ArticleСтатьиРАЗРАБОТКА ТЕХНОЛОГИИ ОЧИСТКИ РЕКОМБИНАНТНОГО СЛИТОГО ПОЛИПЕПТИДА ИЗ КАПСИДНЫХ БЕЛКОВ ВИРУСА ДЕНГЕЛемешеваВ. С.noemail@neicon.ruПоляковД. Н.noemail@neicon.ruСавельевН. С.noemail@neicon.ruПлетюхинаЮ. В.noemail@neicon.ruРабданоС. О.noemail@neicon.ruФГБУ СПбНИИВС ФМБА РоссииRussian Federation202530062025023032Copyright © Лемешева В.С., Поляков Д.Н., Савельев Н.С., Плетюхина Ю.В., Рабдано С.О., 20252025Лемешева В.С., Поляков Д.Н., Савельев Н.С., Плетюхина Ю.В., Рабдано С.О.Лемешева В.С., Поляков Д.Н., Савельев Н.С., Плетюхина Ю.В., Рабдано С.О.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.actbio-vsuet.ru/jour/article/view/5491ReferencesByk L.A., Gamarnik A.V. Properties and functions of the dengue virus capsid protein // Annual Review of Virology. 2016. Vol. 3. № 1. P. 263-281.Byk L.A., Gamarnik A.V. Properties and functions of the dengue virus capsid protein // Annual Review of Virology. 2016. Vol. 3. № 1. P. 263-281.Jonsson C.B., Gallegos J., Fero P. et al. Purification and characterization of the Sin Nombre virus nucleocapsid protein expressed in Escherichia coli // Protein Expression and Purification. 2001. Vol. 23. № 1. P. 134-141.Jonsson C.B., Gallegos J., Fero P. et al. Purification and characterization of the Sin Nombre virus nucleocapsid protein expressed in Escherichia coli // Protein Expression and Purification. 2001. Vol. 23. № 1. P. 134-141.Gil L., Cobas K., Lazo L. et al. A tetravalent formulation based on recombinant nucleocapsid-like particles from dengue viruses induces a functional immune response in mice and monkeys // Journal of Immunology. 2016. Vol. 197. № 9. P. 3597-3606.Gil L., Cobas K., Lazo L. et al. A tetravalent formulation based on recombinant nucleocapsid-like particles from dengue viruses induces a functional immune response in mice and monkeys // Journal of Immunology. 2016. Vol. 197. № 9. P. 3597-3606.Brudenell E.L., Pohare M.B., Zafred D. et al. Efficient overexpression and purification of severe acute respiratory syndrome coronavirus 2 nucleocapsid proteins in Escherichia coli // Biochemical Journal. 2024. Vol. 481. № 11. P. 669-682.Brudenell E.L., Pohare M.B., Zafred D. et al. Efficient overexpression and purification of severe acute respiratory syndrome coronavirus 2 nucleocapsid proteins in Escherichia coli // Biochemical Journal. 2024. Vol. 481. № 11. P. 669-682.Chen C., Zhang Z., Zheng Q. et al. Purification and inhibitor screening of the full-length SARS-CoV-2 nucleocapsid protein // Journal of Immunology. 2025. Vol. 202. № 1. P. 1-10. doi: 10.4049/jimmunol.1600927Chen C., Zhang Z., Zheng Q. et al. Purification and inhibitor screening of the full-length SARS-CoV-2 nucleocapsid protein // Journal of Immunology. 2025. Vol. 202. № 1. P. 1-10. doi: 10.4049/jimmunol.1600927
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