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РЕКОМБИНАНТНЫЕ БЕЛКИ РЕЦЕПТОРА ТИРЕОТРОПНОГО ГОРМОНА, ПОЛУЧЕНИЕ И АНАЛИЗ

https://doi.org/10.20914/2304-4691-2021-1-269-272

About the Authors

А. Зубков
ФГБНУ НИИВС им. И.И. Мечникова
Russian Federation


Н. Кузьмина
ФГБНУ НИИВС им. И.И. Мечникова
Russian Federation


М. Андреева
ФГБНУ НИИВС им. И.И. Мечникова
Russian Federation


А. Сидоров
ФГБНУ НИИВС им. И.И. Мечникова
Russian Federation


Л. Бутова
ФГБНУ НИИВС им. И.И. Мечникова
Russian Federation


References

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2. Furmaniak J., Sanders J., Núñez Miguel R., B. Rees Smith. Mechanisms of Action of TSHR Autoantibodies //Horm Metab Res, 2015; 47: 735-752.

3. Parmentier M., Libert F., Maenhaut C., Lefort A., Gerard C., Perret J., Van Sande J., Dumont J.E., Vassart G. //Molecular cloning of the thyrotropin receptor. Science. 1989; 246 (4937): 1620-1622.

4. Smith T.J. TSHR as a therapeutic target in Graves’ disease. // Expert Opin Ther Targets. 2017; 21(4): 427-432.

5. Rapoport B., McLachlan S.M. TSH receptor cleavage into subunits and shedding of the A-subunit; a molecular and clinical perspective. //Endocrine Reviews, 2016; 37(2): 114-34.

6. Sanders J., Bolton J., Sanders P., Jeffreys J., Nakatake N., Richards T., Evans M., Kiddie A., Summerhayes S., Roberts E., Miguel R.N., Furmaniak J., Smith B.R. Effects of TSH receptor mutations on binding and biological activity of monoclonal antibodies and TSH. // Thyroid. 2007; 17(2): 1195-1206.

7. Gardas A., Watson P.F., Hobby P., Smith A., Weetman A.P., Sutton, B.J. and Banga J.P. Human thyroid peroxidase: mapping of autoantibodies, conformational epitopes to the enzyme surface. //Redox. Rep., 2000; 5, p. 237-241.


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 ,  ,  ,  ,   . Topical biotechnology. 2021;(1):269-272. (In Russ.) https://doi.org/10.20914/2304-4691-2021-1-269-272

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