Preview

Topical biotechnology

Advanced search

РАЗРАБОТКА И ПОЛУЧЕНИЕ ДНК-ИММУНОГЕНА НА ОСНОВЕ ГЕНОВ SARS-COV-2

https://doi.org/10.20914/2304-4691-2021-1-157-159

About the Authors

А. Рябченкова
ООО «АТГ Сервис Ген»
Russian Federation


Е. Чирак
ООО «АТГ Сервис Ген»
Russian Federation


Е. Чирак
ООО «АТГ Сервис Ген»
Russian Federation


Н. Колмаков
ООО «АТГ Сервис Ген»
Russian Federation


И. Духовлинов
ООО «АТГ Сервис Ген»
Russian Federation


References

1. Dey, A. (2021) Immunogenic potential of DNA vaccine candidate, ZyCoV-D against SARS-CoV 2 in animal models. Vaccine, 39(30), 4108-4116.

2. Dhanda, S.K. (2018) Prediction of HLA CD4 immunogenicity in human populations. Front. Immunol., 9, 1369.

3. Dukhovlinov, I.V., Chirak, E.L., Kolmakov, N.N., Fedorova, E.A. and Alekseev, A.V., (2020) Pat. of the Russian Federation № 2747762, PCT/RU2020/000257 appl. 5.04.2020

4. He, Q. (2004) Development of a Western Blot Assay for Detection of Antibodies against Coronavirus Causing Severe Acute Respiratory Syndrome. Clin. Diagn. Lab. Immunol., 11(2), 417-422.

5. Lee, J. (2018) Engineering DNA vaccines against infectious diseases. Acta Biomater., 80, 31-47.

6. Momin, Т. (2021) Safety and Immunogenicity of a DNA SARS-CoV 2 vaccine (ZyCoV-D): Results of an open-label, non-randomized phase I part of phase I/II clinical study by intradermal route in healthy subjects in India. EClinicalMedicine, 38.

7. Rodrigues, João P.G.L.M. (2020) Insights on cross-species transmission of SARS-CoV 2 from structural modeling. PLoS Comput Biol., 16(12).

8. Vojdania, A., Kharrazianb, D. (2020) Potential antigenic cross-reactivity between SARS-CoV 2 and human tissue with a possible link to an increase in autoimmune diseases. Clinical Immunology, 217, 1-2.

9. Williams, J.A. (2010) Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes. Biotechnol Bioeng., 103(6), 1129-1143.

10. Zhao, J. (2020) Antibody responses to SARS-CoV 2 in patients of novel Antibody responses to SARS-CoV 2 in patients of novel coronavirus disease 2019. Clin. Infect. Dis, 71(16), 2027-2034.


Review

For citations:


 ,  ,  ,  ,   . Topical biotechnology. 2021;(1):157-159. (In Russ.) https://doi.org/10.20914/2304-4691-2021-1-157-159

Views: 41


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2304-4691 (Print)