<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actbiotech</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальная биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Topical biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-4691</issn><publisher><publisher-name>ВГУИТ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20914/2304-4691-2023-2-15-18</article-id><article-id custom-type="elpub" pub-id-type="custom">actbiotech-5066</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ПРОТЕКТИВНАЯ АКТИВНОСТЬ БЕСКЛЕТОЧНЫХ КОКЛЮШНЫХ ВАКЦИН НА ОСНОВЕ АНТИГЕННЫХ КОМПЛЕКСОВ, ВЫДЕЛЕННЫХ ИЗ БИОПЛЕНОЧНОЙ И ПЛАНКТОННОЙ КУЛЬТУР BORDETELLA PERTUSSIS</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>Е. М.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Брицина</surname><given-names>М. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Озерецковская</surname><given-names>М. Н.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>А. Е.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБНУ «Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>15</day><month>10</month><year>2023</year></pub-date><volume>0</volume><issue>2</issue><fpage>15</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зайцев Е.М., Брицина М.В., Озерецковская М.Н., Зайцев А.Е., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Зайцев Е.М., Брицина М.В., Озерецковская М.Н., Зайцев А.Е.</copyright-holder><copyright-holder xml:lang="en">Зайцев Е.М., Брицина М.В., Озерецковская М.Н., Зайцев А.Е.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actbio-vsuet.ru/jour/article/view/5066">https://www.actbio-vsuet.ru/jour/article/view/5066</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ломоносова А.В. Причины и последствия несвоевременной вакцинации против коклюшной инфекции в Российской Федерации // Журнал микробиологии, эпидемиологии и иммунобиологии. 2020; 97(5):492 - 52. DOI:https://doi.org/10.36233/0372-9311-2020-97-5-11.</mixed-citation><mixed-citation xml:lang="en">Ломоносова А.В. Причины и последствия несвоевременной вакцинации против коклюшной инфекции в Российской Федерации // Журнал микробиологии, эпидемиологии и иммунобиологии. 2020; 97(5):492 - 52. DOI:https://doi.org/10.36233/0372-9311-2020-97-5-11.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Yeung K.H.T., Duclos P., Nelson E.A.S., et al. An update of the global burden of pertussis in children younger than 5 years: a modelling study // Lancet Infect. Dis. 2017; 17(9):974-980. doi: 10.1016/S1473-3099(17)30390-0.</mixed-citation><mixed-citation xml:lang="en">Yeung K.H.T., Duclos P., Nelson E.A.S., et al. An update of the global burden of pertussis in children younger than 5 years: a modelling study // Lancet Infect. Dis. 2017; 17(9):974-980. doi: 10.1016/S1473-3099(17)30390-0.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Fullen A.R, Yount K.S, Dubey P., et al. Whoop! There it is: The surprising resurgence of pertussis // PLoS Pathog. 2020; 16(7):e1008625. doi:10.1371/journal.ppat.1008625.</mixed-citation><mixed-citation xml:lang="en">Fullen A.R, Yount K.S, Dubey P., et al. Whoop! There it is: The surprising resurgence of pertussis // PLoS Pathog. 2020; 16(7):e1008625. doi:10.1371/journal.ppat.1008625.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Cattelan N., Dubey P., Arnal L. Et al. Bordetella biofilms: a lifestyle leading to persistent infections // Pathog. Dis. 2016; 74(1). DOI: 10.1093/femspd/ftv108.</mixed-citation><mixed-citation xml:lang="en">Cattelan N., Dubey P., Arnal L. Et al. Bordetella biofilms: a lifestyle leading to persistent infections // Pathog. Dis. 2016; 74(1). DOI: 10.1093/femspd/ftv108.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Carriquiriborde F. et al. Vaccine Candidate Based on Outer Membrane Vesicles Derived From Biofilm Culture. Front Immunol. 2021; 12: 730434. doi: 10.3389/fimmu.2021.730434.</mixed-citation><mixed-citation xml:lang="en">Carriquiriborde F. et al. Vaccine Candidate Based on Outer Membrane Vesicles Derived From Biofilm Culture. Front Immunol. 2021; 12: 730434. doi: 10.3389/fimmu.2021.730434.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">МУК 4.2.2317-08 Отбор, проверка и хранение производственных штаммов коклюшных, паракоклюшных и бронхисептикозных бактерий. Москва. 2009].</mixed-citation><mixed-citation xml:lang="en">МУК 4.2.2317-08 Отбор, проверка и хранение производственных штаммов коклюшных, паракоклюшных и бронхисептикозных бактерий. Москва. 2009].</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Зайцев Е.М. и др. Культивирование биопленок Bordetella pertussis на абиотическом субстрате // Журнал микробиологии, эпидемиологии и иммунобиологии. 2019; (1):49-53. DOI:10.36233/0372-9311-2019-1-49-53.</mixed-citation><mixed-citation xml:lang="en">Зайцев Е.М. и др. Культивирование биопленок Bordetella pertussis на абиотическом субстрате // Журнал микробиологии, эпидемиологии и иммунобиологии. 2019; (1):49-53. DOI:10.36233/0372-9311-2019-1-49-53.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Вакцинопрофилактика. 2021; 20(4):68- 72. https://doi.org/10.31631/2073-3046-2021-20-4-68-72</mixed-citation><mixed-citation xml:lang="en">Вакцинопрофилактика. 2021; 20(4):68- 72. https://doi.org/10.31631/2073-3046-2021-20-4-68-72</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ашмарин И.П., Воробьев А.А. Статистические методы в микробиологических исследованиях. Л: 1962.</mixed-citation><mixed-citation xml:lang="en">Ашмарин И.П., Воробьев А.А. Статистические методы в микробиологических исследованиях. Л: 1962.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
