<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actbiotech</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальная биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Topical biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-4691</issn><publisher><publisher-name>ВГУИТ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20914/2304-4691-2021-1-285-286</article-id><article-id custom-type="elpub" pub-id-type="custom">actbiotech-3820</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ФЕРМЕНТЫ БИОСИНТЕЗА ОКСИЛИПИНОВ: ПОЛУЧЕНИЕ И БИОХИМИЧЕСКАЯ ХАРАКТЕРИСТИКА</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горина</surname><given-names>С. С.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мухтарова</surname><given-names>Л. Ш.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Топоркова</surname><given-names>Я. Ю.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гречкин</surname><given-names>А. Н.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Казанский институт биохимии и биофизики</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>285</fpage><lpage>286</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Горина С.С., Мухтарова Л.Ш., Топоркова Я.Ю., Гречкин А.Н., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Горина С.С., Мухтарова Л.Ш., Топоркова Я.Ю., Гречкин А.Н.</copyright-holder><copyright-holder xml:lang="en">Горина С.С., Мухтарова Л.Ш., Топоркова Я.Ю., Гречкин А.Н.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actbio-vsuet.ru/jour/article/view/3820">https://www.actbio-vsuet.ru/jour/article/view/3820</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Andreou A., Brodhun F., Feussner I. Biosynthesis of oxylipins in non-mammals. Prog Lipid Res. 2009. 48, 148-170.</mixed-citation><mixed-citation xml:lang="en">Andreou A., Brodhun F., Feussner I. Biosynthesis of oxylipins in non-mammals. Prog Lipid Res. 2009. 48, 148-170.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Griffiths G. Biosynthesis and analysis of plant oxylipins. Free Radic Res. 2015. 49(5), 565-82.</mixed-citation><mixed-citation xml:lang="en">Griffiths G. Biosynthesis and analysis of plant oxylipins. Free Radic Res. 2015. 49(5), 565-82.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Funk C.D. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001. 294, 1871-1875.</mixed-citation><mixed-citation xml:lang="en">Funk C.D. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001. 294, 1871-1875.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Wasternack C., Hause. Jasmonates: biosynthesis, perception, signal transduction and action in plant stress response, growth and development. An update to the 2007 review in Annals of Botany. Ann Bot. 2013. 111, 1021-58.</mixed-citation><mixed-citation xml:lang="en">Wasternack C., Hause. Jasmonates: biosynthesis, perception, signal transduction and action in plant stress response, growth and development. An update to the 2007 review in Annals of Botany. Ann Bot. 2013. 111, 1021-58.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Griffiths G. Jasmonates: biosynthesis, perception and signal transduction. Essays Biochem. 2020. 23, 501-512.</mixed-citation><mixed-citation xml:lang="en">Griffiths G. Jasmonates: biosynthesis, perception and signal transduction. Essays Biochem. 2020. 23, 501-512.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Christensen S.A., Kolomiets M.V. The lipid language of plant-fungal interactions. Fungal Genet Biol. 2011.48(1), 4-14.</mixed-citation><mixed-citation xml:lang="en">Christensen S.A., Kolomiets M.V. The lipid language of plant-fungal interactions. Fungal Genet Biol. 2011.48(1), 4-14.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gessler N.N., Filippovich S.Y., Bachurina G.P., Kharchenko E.A., Groza N.V., Belozerskaya T.A. Oxylipins and oxylipin synthesis pathways in fungi. Applied Biochemistry and Microbiology. 2017. 53, 628-639.</mixed-citation><mixed-citation xml:lang="en">Gessler N.N., Filippovich S.Y., Bachurina G.P., Kharchenko E.A., Groza N.V., Belozerskaya T.A. Oxylipins and oxylipin synthesis pathways in fungi. Applied Biochemistry and Microbiology. 2017. 53, 628-639.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Bouarab K., Adas F., Gaquerel E., Kloareg B., Salaün J.P., Potin P. The Innate Immunity of a Marine Red Alga Involves Oxylipins from Both the Eicosanoid and Octadecanoid Pathways. Plant Physiol. 2004.135(3), 1838-48.</mixed-citation><mixed-citation xml:lang="en">Bouarab K., Adas F., Gaquerel E., Kloareg B., Salaün J.P., Potin P. The Innate Immunity of a Marine Red Alga Involves Oxylipins from Both the Eicosanoid and Octadecanoid Pathways. Plant Physiol. 2004.135(3), 1838-48.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Meyer N., Rettner J., Werner M., Werz O., Pohnert G. Algal Oxylipins Mediate the Resistance of Diatoms against Algicidal Bacteria. Mar Drugs. 2018.16(12), 486.</mixed-citation><mixed-citation xml:lang="en">Meyer N., Rettner J., Werner M., Werz O., Pohnert G. Algal Oxylipins Mediate the Resistance of Diatoms against Algicidal Bacteria. Mar Drugs. 2018.16(12), 486.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Feussner I., Wasternack C. The Lipoxygenase pathway. Annual Review of Plant Biology. 2002. 53, 275-297.</mixed-citation><mixed-citation xml:lang="en">Feussner I., Wasternack C. The Lipoxygenase pathway. Annual Review of Plant Biology. 2002. 53, 275-297.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Gorina S.S., Toporkova Y.Y., Mukhtarova L.S., Chechetkin I.R., Khairutdinov B.I., Gogolev Y.V., Grechkin A.N. Detection and molecular cloning of CYP74Q1 gene: identification of Ranunculus acris leaf divinyl ether synthase. Biochim Biophys Acta. 2014 1841(9), 1227-33.</mixed-citation><mixed-citation xml:lang="en">Gorina S.S., Toporkova Y.Y., Mukhtarova L.S., Chechetkin I.R., Khairutdinov B.I., Gogolev Y.V., Grechkin A.N. Detection and molecular cloning of CYP74Q1 gene: identification of Ranunculus acris leaf divinyl ether synthase. Biochim Biophys Acta. 2014 1841(9), 1227-33.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Gorina S.S., Toporkova Y.Y., Mukhtarova L.S., Smirnova E.O., Chechetkin I.R., Khairutdinov B.I., Gogolev Y.V., Grechkin A.N. Oxylipin biosynthesis in spikemoss Selaginella moellendorffii: Molecular cloning and identification of divinyl ether synthases CYP74M1 and CYP74M3. Biochim Biophys Acta. 2016. 1861(4), 301-309.</mixed-citation><mixed-citation xml:lang="en">Gorina S.S., Toporkova Y.Y., Mukhtarova L.S., Smirnova E.O., Chechetkin I.R., Khairutdinov B.I., Gogolev Y.V., Grechkin A.N. Oxylipin biosynthesis in spikemoss Selaginella moellendorffii: Molecular cloning and identification of divinyl ether synthases CYP74M1 and CYP74M3. Biochim Biophys Acta. 2016. 1861(4), 301-309.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Toporkova Y.Y., Fatykhova V.S., Gorina S.S., Mukhtarova L.S., Grechkin A.N. Epoxyalcohol Synthase RjEAS (CYP74A88) from the Japanese Buttercup (Ranunculus japonicus): Cloning and Characterization of Catalytic Properties. Biochemistry (Mosc). 2019.84(2), 171-180.</mixed-citation><mixed-citation xml:lang="en">Toporkova Y.Y., Fatykhova V.S., Gorina S.S., Mukhtarova L.S., Grechkin A.N. Epoxyalcohol Synthase RjEAS (CYP74A88) from the Japanese Buttercup (Ranunculus japonicus): Cloning and Characterization of Catalytic Properties. Biochemistry (Mosc). 2019.84(2), 171-180.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Toporkova Y.Y., Smirnova E.O., Gorina S.S., Mukhtarova L.S., Grechkin A.N. Detection of the first higher plant epoxyalcohol synthase: Molecular cloning and characterisation of the CYP74M2 enzyme of spikemoss Selaginella moellendorffii. Phytochemistry. 2018. 156, 73-82.</mixed-citation><mixed-citation xml:lang="en">Toporkova Y.Y., Smirnova E.O., Gorina S.S., Mukhtarova L.S., Grechkin A.N. Detection of the first higher plant epoxyalcohol synthase: Molecular cloning and characterisation of the CYP74M2 enzyme of spikemoss Selaginella moellendorffii. Phytochemistry. 2018. 156, 73-82.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Toporkova Y.Y., Gorina S.S., Bessolitsyna E.K., Smirnova E.O., Fatykhova V.S., Brühlmann F., Ilyina T.M., Mukhtarova L.S., Grechkin A.N. Double function hydroperoxide lyases / epoxyalcohol synthases (CYP74C) of higher plants: identification and conversion into allene oxide synthases by site-directed mutagenesis. Biochim Biophys Acta. 2018. 1863(4), 369-378.</mixed-citation><mixed-citation xml:lang="en">Toporkova Y.Y., Gorina S.S., Bessolitsyna E.K., Smirnova E.O., Fatykhova V.S., Brühlmann F., Ilyina T.M., Mukhtarova L.S., Grechkin A.N. Double function hydroperoxide lyases / epoxyalcohol synthases (CYP74C) of higher plants: identification and conversion into allene oxide synthases by site-directed mutagenesis. Biochim Biophys Acta. 2018. 1863(4), 369-378.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Toporkova Y.Y., Ermilova V.S., Gorina S.S., Mukhtarova L.S., Osipova E.V., Gogolev Y.V., Grechkin A.N. Structure- function relationship in the CYP74 family: conversion of divinyl ether synthases into allene oxide synthases by site-directed mutagenesis. FEBS Lett. 2013 587(16), 2552-2558.</mixed-citation><mixed-citation xml:lang="en">Toporkova Y.Y., Ermilova V.S., Gorina S.S., Mukhtarova L.S., Osipova E.V., Gogolev Y.V., Grechkin A.N. Structure- function relationship in the CYP74 family: conversion of divinyl ether synthases into allene oxide synthases by site-directed mutagenesis. FEBS Lett. 2013 587(16), 2552-2558.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Brash A.R. Mechanistic aspects of CYP74 allene oxide synthases and related cytochrome P450 enzymes. Phytochemistry. 2009. 70, 1522-1531.</mixed-citation><mixed-citation xml:lang="en">Brash A.R. Mechanistic aspects of CYP74 allene oxide synthases and related cytochrome P450 enzymes. Phytochemistry. 2009. 70, 1522-1531.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Boeglin W.E., Brash A.R. Cytochrome P450-type Hydroxylation and Epoxidation in a Tyrosine-liganded Hemoprotein, Catalase-related Allene Oxide Synthase J Biol Chem, 2012. 287, 24139-24147.</mixed-citation><mixed-citation xml:lang="en">Boeglin W.E., Brash A.R. Cytochrome P450-type Hydroxylation and Epoxidation in a Tyrosine-liganded Hemoprotein, Catalase-related Allene Oxide Synthase J Biol Chem, 2012. 287, 24139-24147.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Oliw E.H., Hamberg M. An allene oxide and 12-oxophytodienoic acid are key intermediates in jasmonic acid biosynthesis by Fusarium oxysporum J Lipid Res. 2017. 58(8), 1670-1680.</mixed-citation><mixed-citation xml:lang="en">Oliw E.H., Hamberg M. An allene oxide and 12-oxophytodienoic acid are key intermediates in jasmonic acid biosynthesis by Fusarium oxysporum J Lipid Res. 2017. 58(8), 1670-1680.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
