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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actbiotech</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальная биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Topical biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-4691</issn><publisher><publisher-name>ВГУИТ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20914/2304-4691-2021-1-224-228</article-id><article-id custom-type="elpub" pub-id-type="custom">actbiotech-3783</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>КИНЕТИЧЕСКИЙ ПОДХОД К ФОРМИРОВАНИЮ ДВУХМЕДИАТОРНЫХ СИСТЕМ ДЛЯ СОЗДАНИЯ МИКРОБНЫХ БИОСЕНСОРОВ НА ПРИМЕРЕ ЭКСПРЕСС-АНАЛИЗА ИНДЕКСА БИОХИМИЧЕСКОГО ПОТРЕБЛЕНИЯ КИСЛОРОДА</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арляпов</surname><given-names>В. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Харькова</surname><given-names>А. С.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Илюхина</surname><given-names>А. С.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Тульский государственный университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>224</fpage><lpage>228</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Арляпов В.А., Харькова А.С., Илюхина А.С., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Арляпов В.А., Харькова А.С., Илюхина А.С.</copyright-holder><copyright-holder xml:lang="en">Арляпов В.А., Харькова А.С., Илюхина А.С.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actbio-vsuet.ru/jour/article/view/3783">https://www.actbio-vsuet.ru/jour/article/view/3783</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ejeian F., Etedali P., Mansouri-Tehrani H.A., Soozanipour A., Low Z.X., Asadnia M., Taheri-Kafrani A., Razmjou A. Biosensors for wastewater monitoring: A review //Biosensors and Bioelectronics. - 2018. - V. 118. - PP. 66-79.</mixed-citation><mixed-citation xml:lang="en">Ejeian F., Etedali P., Mansouri-Tehrani H.A., Soozanipour A., Low Z.X., Asadnia M., Taheri-Kafrani A., Razmjou A. Biosensors for wastewater monitoring: A review //Biosensors and Bioelectronics. - 2018. - V. 118. - PP. 66-79.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">ISO 5815-1:2003, 2003. Water Quality - Determination of Biochemical Oxygen Demand after N Days (BODn) - Part 1: Dilution and Seeding Method with Allylthiourea Addition.</mixed-citation><mixed-citation xml:lang="en">ISO 5815-1:2003, 2003. Water Quality - Determination of Biochemical Oxygen Demand after N Days (BODn) - Part 1: Dilution and Seeding Method with Allylthiourea Addition.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Niyomdecha S., Limbut W., Numnuam A., Asawatreratanakul P., Kanatharana P., Thavarungkula P. A novel BOD biosensor based on entrapped activated sludge in aporous chitosan-albumin cryogel incorporated with graphene andmethylene blue //Sensors and Actuators B: Chemical. - 2017. - V. 241. - P. 473-481.</mixed-citation><mixed-citation xml:lang="en">Niyomdecha S., Limbut W., Numnuam A., Asawatreratanakul P., Kanatharana P., Thavarungkula P. A novel BOD biosensor based on entrapped activated sludge in aporous chitosan-albumin cryogel incorporated with graphene andmethylene blue //Sensors and Actuators B: Chemical. - 2017. - V. 241. - P. 473-481.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Hu J., Li Y., Gao G., Xia S. A Mediated BOD Biosensor Based on Immobilized B. Subtilis on Three-Dimensional Porous Graphene-Polypyrrole Composite //Sensors. - 2017. - V. 17. - №. 11. - P. 2594.</mixed-citation><mixed-citation xml:lang="en">Hu J., Li Y., Gao G., Xia S. A Mediated BOD Biosensor Based on Immobilized B. Subtilis on Three-Dimensional Porous Graphene-Polypyrrole Composite //Sensors. - 2017. - V. 17. - №. 11. - P. 2594.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Rawson F, Gross A, Garrett D, Downard A, Baronian K. Mediated electrochemical detection of electron transfer from the outer surface of the cell wall of Saccharomyces cerevisiae //Electrochemistry Communications. - 2012. - V. 15. - №. 1. - P. 85-87.</mixed-citation><mixed-citation xml:lang="en">Rawson F, Gross A, Garrett D, Downard A, Baronian K. Mediated electrochemical detection of electron transfer from the outer surface of the cell wall of Saccharomyces cerevisiae //Electrochemistry Communications. - 2012. - V. 15. - №. 1. - P. 85-87.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Zaitseva A.S., Arlyapov V.A., Yudina N. Yu., Alferov S.V., Reshetilov A.N. Use of one - and two-mediator systems for developing a BOD biosensor based on the yeast Debaryomyces hansenii // Enzyme and Microbial Technology. - 2017. - V. 98. - P. 43-51.</mixed-citation><mixed-citation xml:lang="en">Zaitseva A.S., Arlyapov V.A., Yudina N. Yu., Alferov S.V., Reshetilov A.N. Use of one - and two-mediator systems for developing a BOD biosensor based on the yeast Debaryomyces hansenii // Enzyme and Microbial Technology. - 2017. - V. 98. - P. 43-51.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gao G., Fang D., Yu Y., Wu L., Wang Y., Zhi J. A double-mediator based whole cell electrochemical biosensor for acute biotoxicity assessment of wastewater //Talanta. - 2017. - V. 167. - P. 208-216.</mixed-citation><mixed-citation xml:lang="en">Gao G., Fang D., Yu Y., Wu L., Wang Y., Zhi J. A double-mediator based whole cell electrochemical biosensor for acute biotoxicity assessment of wastewater //Talanta. - 2017. - V. 167. - P. 208-216.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Chan C., Lehmann M., Tag K., Lung M., Kunze G., Riedeld K., Gruendige B., Renneberg R. Measurement of biodegradable substances using the salt-tolerant yeast Arxula adeninivorans for a microbial sensor immobilized with poly(carbamoyl)sulfonate (PCS). Part II: Application of the novel biosensor to real samples from coastal and island regions. // Biosens Bioelectron. - 1999. - V.14. - I. 3. - PP. 295-302.</mixed-citation><mixed-citation xml:lang="en">Chan C., Lehmann M., Tag K., Lung M., Kunze G., Riedeld K., Gruendige B., Renneberg R. Measurement of biodegradable substances using the salt-tolerant yeast Arxula adeninivorans for a microbial sensor immobilized with poly(carbamoyl)sulfonate (PCS). Part II: Application of the novel biosensor to real samples from coastal and island regions. // Biosens Bioelectron. - 1999. - V.14. - I. 3. - PP. 295-302.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Nicholson R.S., Shain I. Theory of stationary electrode polarography. Single scan and cyclic methods applied to reversible, irreversible, and kinetic systems //Analytical Chemistry. - 1964. - V. 36. - №. 4. - P. 706-723.</mixed-citation><mixed-citation xml:lang="en">Nicholson R.S., Shain I. Theory of stationary electrode polarography. Single scan and cyclic methods applied to reversible, irreversible, and kinetic systems //Analytical Chemistry. - 1964. - V. 36. - №. 4. - P. 706-723.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Kharkova A.S., Arlyapov V.A., Turovskaya A.D., Shvets V.I., Reshetilov A.N. A mediator microbial biosensor for assaying general toxicity. // Enzyme and Microbial Technology. - 2020. - V. 132.</mixed-citation><mixed-citation xml:lang="en">Kharkova A.S., Arlyapov V.A., Turovskaya A.D., Shvets V.I., Reshetilov A.N. A mediator microbial biosensor for assaying general toxicity. // Enzyme and Microbial Technology. - 2020. - V. 132.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
