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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actbiotech</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальная биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Topical biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-4691</issn><publisher><publisher-name>ВГУИТ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20914/2304-4691-2021-1-154-156</article-id><article-id custom-type="elpub" pub-id-type="custom">actbiotech-3752</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>БИОРАСПРЕДЕЛЕНИЕ ДНК-ИММУНОГЕНА НА ОСНОВЕ ГЕНОВ КОРОНАВИРУСА SARS-COV-2</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рябченкова</surname><given-names>А. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чирак</surname><given-names>Е. Р.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чирак</surname><given-names>Е. Л.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колмаков</surname><given-names>Н. Н.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Духовлинов</surname><given-names>И. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ООО «АТГ Сервис Ген»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>154</fpage><lpage>156</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рябченкова А.А., Чирак Е.Р., Чирак Е.Л., Колмаков Н.Н., Духовлинов И.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Рябченкова А.А., Чирак Е.Р., Чирак Е.Л., Колмаков Н.Н., Духовлинов И.В.</copyright-holder><copyright-holder xml:lang="en">Рябченкова А.А., Чирак Е.Р., Чирак Е.Л., Колмаков Н.Н., Духовлинов И.В.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actbio-vsuet.ru/jour/article/view/3752">https://www.actbio-vsuet.ru/jour/article/view/3752</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dukhovlinov, I.V., Chirak, E.L., Kolmakov, N.N., Fedorova, E.A. and Alekseev, A.V., (2020) Pat. of the Russian Federation № 2747762, PCT/RU2020/000257 appl. 5.04.2020</mixed-citation><mixed-citation xml:lang="en">Dukhovlinov, I.V., Chirak, E.L., Kolmakov, N.N., Fedorova, E.A. and Alekseev, A.V., (2020) Pat. of the Russian Federation № 2747762, PCT/RU2020/000257 appl. 5.04.2020</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Houk B E, Martin R, Hochhaus G and Hughes J A 2013 Pharmacokinetics of Plasmid DNA in the Rat Molecular Biology 25 pp 641-646</mixed-citation><mixed-citation xml:lang="en">Houk B E, Martin R, Hochhaus G and Hughes J A 2013 Pharmacokinetics of Plasmid DNA in the Rat Molecular Biology 25 pp 641-646</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Koressaar T and Remm M 2007 Enhancements and modifications of primer design program Primer3 Bioinformatics 23(10) pp 1289-1291</mixed-citation><mixed-citation xml:lang="en">Koressaar T and Remm M 2007 Enhancements and modifications of primer design program Primer3 Bioinformatics 23(10) pp 1289-1291</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Liu C, Fan M, Xu Q and Li Y 2008 Biodistribution and expression of targeted fusion anti-caries DNA vaccine pGJA-P/VAX in mice J Gene Med. 10 pp 298-305</mixed-citation><mixed-citation xml:lang="en">Liu C, Fan M, Xu Q and Li Y 2008 Biodistribution and expression of targeted fusion anti-caries DNA vaccine pGJA-P/VAX in mice J Gene Med. 10 pp 298-305</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Palumbo R N, Zhong X, Panus D, Han W, Ji W and Wang C 2012 Transgene expression and local tissue distribution of naked and polymer-condensed plasmid DNA after intradermal administration in mice J of Controlled Release 159 pp 232-239</mixed-citation><mixed-citation xml:lang="en">Palumbo R N, Zhong X, Panus D, Han W, Ji W and Wang C 2012 Transgene expression and local tissue distribution of naked and polymer-condensed plasmid DNA after intradermal administration in mice J of Controlled Release 159 pp 232-239</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Rivest S 2009 Regulation of innate immune responses in the brain Nat. Rev. Immunol. 9(6) pp 429-439</mixed-citation><mixed-citation xml:lang="en">Rivest S 2009 Regulation of innate immune responses in the brain Nat. Rev. Immunol. 9(6) pp 429-439</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
