<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actbiotech</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальная биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Topical biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-4691</issn><publisher><publisher-name>ВГУИТ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20914/2304-4691-2021-1-140</article-id><article-id custom-type="elpub" pub-id-type="custom">actbiotech-3745</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ДИНАМИКА АНТИТЕЛОБРАЗОВАНИЯ И ИЗОТИПЫ АНТИТЕЛ В ИММУННОМ ОТВЕТЕ МЫШЕЙ BALB/C НА S БЕЛОК ВИРУСА SARS-COV-2</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кан</surname><given-names>В. Ю.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бидина</surname><given-names>А. Д.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ожаровская</surname><given-names>А. Т.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воронина</surname><given-names>Д. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зубкова</surname><given-names>О. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИЦЭМ им. Н.Ф. Гамалеи Минздрава России</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>140</fpage><lpage>140</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кан В.Ю., Бидина А.Д., Ожаровская А.Т., Воронина Д.В., Зубкова О.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Кан В.Ю., Бидина А.Д., Ожаровская А.Т., Воронина Д.В., Зубкова О.В.</copyright-holder><copyright-holder xml:lang="en">Кан В.Ю., Бидина А.Д., Ожаровская А.Т., Воронина Д.В., Зубкова О.В.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actbio-vsuet.ru/jour/article/view/3745">https://www.actbio-vsuet.ru/jour/article/view/3745</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sahin U, Muik A, Derhovanessian E, Vogler I, Kranz LM, Vormehr M, et al. COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses. Nature. 2020; 586(7830):594-9.</mixed-citation><mixed-citation xml:lang="en">Sahin U, Muik A, Derhovanessian E, Vogler I, Kranz LM, Vormehr M, et al. COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses. Nature. 2020; 586(7830):594-9.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Visciano, M.L., Tagliamonte, M., Tornesello, M.L. et al. Effects of adjuvants on IgG subclasses elicited by virus-like Particles. J Transl Med 10, 4 (2012).</mixed-citation><mixed-citation xml:lang="en">Visciano, M.L., Tagliamonte, M., Tornesello, M.L. et al. Effects of adjuvants on IgG subclasses elicited by virus-like Particles. J Transl Med 10, 4 (2012).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Harshad P. Patil, Prajakta S. Rane, Shubham Shrivastava, Sonali Palkar, Sanjay Lalwani, Akhilesh C. Mishra, and Vidya A. Arankalle. Viral Immunology. Apr 2021. 201-209.</mixed-citation><mixed-citation xml:lang="en">Harshad P. Patil, Prajakta S. Rane, Shubham Shrivastava, Sonali Palkar, Sanjay Lalwani, Akhilesh C. Mishra, and Vidya A. Arankalle. Viral Immunology. Apr 2021. 201-209.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Yun Shan Goh, Jean-Marc Chavatte, Alicia Lim Jieling, Bernett Lee, Pei Xiang Hor, Sensitive detection of total anti-Spike antibodies and isotype switching in asymptomatic and symptomatic individuals with COVID-19, Cell Reports Medicine. Feb 2021.</mixed-citation><mixed-citation xml:lang="en">Yun Shan Goh, Jean-Marc Chavatte, Alicia Lim Jieling, Bernett Lee, Pei Xiang Hor, Sensitive detection of total anti-Spike antibodies and isotype switching in asymptomatic and symptomatic individuals with COVID-19, Cell Reports Medicine. Feb 2021.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
