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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actbiotech</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальная биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Topical biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-4691</issn><publisher><publisher-name>ВГУИТ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20914/2304-4691-2021-1-134-138</article-id><article-id custom-type="elpub" pub-id-type="custom">actbiotech-3743</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>УПРАВЛЕНИЕ ПРОФИЛЕМ ВЫСВОБОЖДЕНИЯ ДОКСОРУБИЦИНА ИЗ НАНОРАЗМЕРНОЙ ЛЕКАРСТВЕННОЙ ФОРМЫ НА ОСНОВЕ СОПОЛИМЕРА МОЛОЧНОЙ И ГЛИКОЛЕВОЙ КИСЛОТ (PLGA)</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермоленко</surname><given-names>Ю. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Назарова</surname><given-names>Н. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осипова</surname><given-names>Н. С.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ковшова</surname><given-names>Т. С.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гельперина</surname><given-names>С. Э.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Российский химико-технологический университет им. Д.И. Менделеева</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>134</fpage><lpage>138</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ермоленко Ю.В., Назарова Н.А., Осипова Н.С., Ковшова Т.С., Гельперина С.Э., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Ермоленко Ю.В., Назарова Н.А., Осипова Н.С., Ковшова Т.С., Гельперина С.Э.</copyright-holder><copyright-holder xml:lang="en">Ермоленко Ю.В., Назарова Н.А., Осипова Н.С., Ковшова Т.С., Гельперина С.Э.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actbio-vsuet.ru/jour/article/view/3743">https://www.actbio-vsuet.ru/jour/article/view/3743</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гельперина С.Э. и Швец В.И. 2009 Системы доставки лекарственных веществ на основе полимерных наночастиц Биотехнология 3 8-23</mixed-citation><mixed-citation xml:lang="en">Гельперина С.Э. и Швец В.И. 2009 Системы доставки лекарственных веществ на основе полимерных наночастиц Биотехнология 3 8-23</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bala I., Hariharan S. and Kumar R. 2004 PLGA Nanoparticles in Drug Delivery: The State of the Art Critical Reviews in therapeutic Drug Carrier Systems 21(5) 387-422</mixed-citation><mixed-citation xml:lang="en">Bala I., Hariharan S. and Kumar R. 2004 PLGA Nanoparticles in Drug Delivery: The State of the Art Critical Reviews in therapeutic Drug Carrier Systems 21(5) 387-422</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Rezvantalab S., Drude N.I., Moraveji1 M.K., Güvener N., Koons E.K., Shi Y, Lammers T and Kiessling F. 2018 PLGA-Based Nanoparticles in Cancer Treatment Fronters in Pharmacology 9 1260</mixed-citation><mixed-citation xml:lang="en">Rezvantalab S., Drude N.I., Moraveji1 M.K., Güvener N., Koons E.K., Shi Y, Lammers T and Kiessling F. 2018 PLGA-Based Nanoparticles in Cancer Treatment Fronters in Pharmacology 9 1260</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Gupta P.N., Jain Sh., Nehate Sh., Alam N., Khare V., Dubey R.D., Saneja A., Kour S., Singh Sh. 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