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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">actbiotech</journal-id><journal-title-group><journal-title xml:lang="ru">Актуальная биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Topical biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-4691</issn><publisher><publisher-name>ВГУИТ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20914/2304-4691-2022-1-124-127</article-id><article-id custom-type="elpub" pub-id-type="custom">actbiotech-346</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ГЕНО-ФЕНОТИПИЧЕСКИЕ МАРКЕРЫ ВИРУЛЕНТНОСТИ И АНТИБИОТИКОРЕЗИСТЕНТНОСТИ МИКРОБИОТЫ ВЫСОКИХ ШИРОТ</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панин</surname><given-names>А. Л.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Краева</surname><given-names>Л. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сбойчаков</surname><given-names>В. Б.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гончаров</surname><given-names>Н. Е.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белов</surname><given-names>А. Б.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГУН «Санкт-Петербургский НИИ эпидемиологии и микробиологии имени Пастера»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>26</day><month>09</month><year>2022</year></pub-date><volume>0</volume><issue>1</issue><fpage>124</fpage><lpage>127</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Панин А.Л., Краева Л.А., Сбойчаков В.Б., Гончаров Н.Е., Белов А.Б., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Панин А.Л., Краева Л.А., Сбойчаков В.Б., Гончаров Н.Е., Белов А.Б.</copyright-holder><copyright-holder xml:lang="en">Панин А.Л., Краева Л.А., Сбойчаков В.Б., Гончаров Н.Е., Белов А.Б.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.actbio-vsuet.ru/jour/article/view/346">https://www.actbio-vsuet.ru/jour/article/view/346</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бурганская, Е.И. Аноксигенные нитчатые фототрофные бактерии в микробных сообществах минерализованных водных экосистем / Е.И. Бурганская: Дисс… канд. биол. наук. -М., 2020. -169 с.</mixed-citation><mixed-citation xml:lang="en">Бурганская, Е.И. Аноксигенные нитчатые фототрофные бактерии в микробных сообществах минерализованных водных экосистем / Е.И. Бурганская: Дисс… канд. биол. наук. -М., 2020. -169 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Гончаров, А.Е. Идентификация фрагмента острова высокой патогенности иерсиний у госпитальных штаммов энтеробактерий / А.Е. Гончаров, В.Ю. Хорошилова, Л.П. Зуева // Профилактическая и клиническая медицина. -2013. -№ 1, т. 13. -С. 66-68.</mixed-citation><mixed-citation xml:lang="en">Гончаров, А.Е. Идентификация фрагмента острова высокой патогенности иерсиний у госпитальных штаммов энтеробактерий / А.Е. Гончаров, В.Ю. Хорошилова, Л.П. Зуева // Профилактическая и клиническая медицина. -2013. -№ 1, т. 13. -С. 66-68.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Гуреева, М.В. Экология микроорганизмов / М.В. Гуреева, М.Ю. Грабович. -Воронеж, 2021: изд. домВЛГУ. -107 с.</mixed-citation><mixed-citation xml:lang="en">Гуреева, М.В. Экология микроорганизмов / М.В. Гуреева, М.Ю. Грабович. -Воронеж, 2021: изд. домВЛГУ. -107 с.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Климов, В.Т. Молекулярно -генетический мониторинг на основеПЦР О -генотипирования / В.Т. Климов, М.В.</mixed-citation><mixed-citation xml:lang="en">Климов, В.Т. Молекулярно -генетический мониторинг на основеПЦР О -генотипирования / В.Т. Климов, М.В.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Чеснокова // Молекулярная генетика. -2007. -№ 4. -С. 14-17.</mixed-citation><mixed-citation xml:lang="en">Чеснокова // Молекулярная генетика. -2007. -№ 4. -С. 14-17.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Королюк, А.М. Диагностическая ценностьПЦР при иерсиниозах / А.М. Королюк, Н.В. Михайлов, И.В.</mixed-citation><mixed-citation xml:lang="en">Королюк, А.М. Диагностическая ценностьПЦР при иерсиниозах / А.М. Королюк, Н.В. Михайлов, И.В.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Мирошниченко // МатериалыVII съезда Всероссийского общества эпидемиологов, микробиологов, паразитологов. -М., 1997. -С. 180-181.</mixed-citation><mixed-citation xml:lang="en">Мирошниченко // МатериалыVII съезда Всероссийского общества эпидемиологов, микробиологов, паразитологов. -М., 1997. -С. 180-181.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Крыленков, В.А. Микробиота земной криосферы / В.А. Крыленков, А.Е. Гончаров //СПб.: Фолиант, 2019. -448 с.</mixed-citation><mixed-citation xml:lang="en">Крыленков, В.А. Микробиота земной криосферы / В.А. Крыленков, А.Е. Гончаров //СПб.: Фолиант, 2019. -448 с.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Сбойчаков, В.Б. Цианобактерии как биологические индикаторы глобального потепления / В.Б. Сбойчаков, А.Л. Панин // Актуальная биотехнология. -2020. -№ 3 (34). -С. 465-469.</mixed-citation><mixed-citation xml:lang="en">Сбойчаков, В.Б. Цианобактерии как биологические индикаторы глобального потепления / В.Б. Сбойчаков, А.Л. Панин // Актуальная биотехнология. -2020. -№ 3 (34). -С. 465-469.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ahmed, E. Siderophores in environmental research: roles and applications / E. Ahmed, S.J.M. Holmstrom // Microbial biotechnology. -2014. -Vol.7, № 3. -P. 196-208.</mixed-citation><mixed-citation xml:lang="en">Ahmed, E. Siderophores in environmental research: roles and applications / E. Ahmed, S.J.M. Holmstrom // Microbial biotechnology. -2014. -Vol.7, № 3. -P. 196-208.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Aminov, R.I. Evolution and ecology of antibiotic resistance genes / R.I. Aminov, R.I. Mackie //FEMS microbiology letters. - 2007. -Vol. 271, № 2. -P. 147-161.</mixed-citation><mixed-citation xml:lang="en">Aminov, R.I. Evolution and ecology of antibiotic resistance genes / R.I. Aminov, R.I. Mackie //FEMS microbiology letters. - 2007. -Vol. 271, № 2. -P. 147-161.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Bidle, K.D. Fossil genes and microbes in the oldest ice on Earth / K.D. Bidle, S. Lee, D.R. Marchant, P.G. Falkowski // Proceedings of the National Academy of Science. -2007. -Vol. 104, № 33. -P.13455-13460.</mixed-citation><mixed-citation xml:lang="en">Bidle, K.D. Fossil genes and microbes in the oldest ice on Earth / K.D. Bidle, S. Lee, D.R. Marchant, P.G. Falkowski // Proceedings of the National Academy of Science. -2007. -Vol. 104, № 33. -P.13455-13460.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Carniel, E. The Yersinia high-pathogenicity island: an iron-uptakeisland / E. Carniel // Microbes Infect. -2001. -Vol. 3, № 7. - P. 561-569.</mixed-citation><mixed-citation xml:lang="en">Carniel, E. The Yersinia high-pathogenicity island: an iron-uptakeisland / E. Carniel // Microbes Infect. -2001. -Vol. 3, № 7. - P. 561-569.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Collyn, F.YAPI, a new Yesinia pseudotuberculosis pathogenicity island / F. Collyn, A. Billault, C. Mullet // Infect. Immunol. - 2004. -Vol. 72. -P. 4784-4790.</mixed-citation><mixed-citation xml:lang="en">Collyn, F.YAPI, a new Yesinia pseudotuberculosis pathogenicity island / F. Collyn, A. Billault, C. Mullet // Infect. Immunol. - 2004. -Vol. 72. -P. 4784-4790.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Dandachi, I. Prevalence and Characterization of Multi-Drug-Resistant Gram-Negative Bacilli Isolated From Lebanese Poultry: A Nationwide Study / I. Dandachi, E.S. Sokhn, E.A. Dahdouh et al. // Frontiers in Microbiology. -2018. -№ 3(23). -Р.550. https://doi.org/10.3389/fmicb.2018.00550</mixed-citation><mixed-citation xml:lang="en">Dandachi, I. Prevalence and Characterization of Multi-Drug-Resistant Gram-Negative Bacilli Isolated From Lebanese Poultry: A Nationwide Study / I. Dandachi, E.S. Sokhn, E.A. Dahdouh et al. // Frontiers in Microbiology. -2018. -№ 3(23). -Р.550. https://doi.org/10.3389/fmicb.2018.00550</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">De Keukeleire, S. Yersinia ruckeri, an unusual microorganism isolated from a human wound infection / S. De Keukeleire // New Microbes New Infect. -2014. -Vol.2, № 4. -P. 134-135. doi: 10.1002/nmi2.56.</mixed-citation><mixed-citation xml:lang="en">De Keukeleire, S. Yersinia ruckeri, an unusual microorganism isolated from a human wound infection / S. De Keukeleire // New Microbes New Infect. -2014. -Vol.2, № 4. -P. 134-135. doi: 10.1002/nmi2.56.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Frank-Fahle, B.A. Microbial functional potential and community composition in permafrost-affected soils of theNW Canadian Arctic / B.A. Frank-Fahle, E. Yergeau, C.W. Greer //PLoS One. -2014. -Vol.9, № 1. -e84761. Doi: org/10.1371/journal.pone.0084761.</mixed-citation><mixed-citation xml:lang="en">Frank-Fahle, B.A. Microbial functional potential and community composition in permafrost-affected soils of theNW Canadian Arctic / B.A. Frank-Fahle, E. Yergeau, C.W. Greer //PLoS One. -2014. -Vol.9, № 1. -e84761. Doi: org/10.1371/journal.pone.0084761.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Frey, B. Microbial diversity in European alpine permafrost and active layers / B. Frey, T. Rime, M. Phillips //FEMS microbiology ecology. -2016. -Vol. 92, -№ 3. P. 1-35.</mixed-citation><mixed-citation xml:lang="en">Frey, B. Microbial diversity in European alpine permafrost and active layers / B. Frey, T. Rime, M. Phillips //FEMS microbiology ecology. -2016. -Vol. 92, -№ 3. P. 1-35.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Hwengwere, К. Antimicrobial resistance in Antarctica: is it still a pristine environment? / K. Hwengwere, H. Paramel, K.A. Hughes et al. // Microbiome. -2022. -Vol. 10(71). https://doi.org/10.1186/s40168-022-01250-x.</mixed-citation><mixed-citation xml:lang="en">Hwengwere, К. Antimicrobial resistance in Antarctica: is it still a pristine environment? / K. Hwengwere, H. Paramel, K.A. Hughes et al. // Microbiome. -2022. -Vol. 10(71). https://doi.org/10.1186/s40168-022-01250-x.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Ishimaru, C.A. High-affinity iron uptake systems present in Erwinia carotovora subsp. carotovora include the hydroxamate siderophore aerobactin / C.A. Ishimaru, J.E. Loper // Journal of bacteriology. -1992. -T. 174, № 9. -P. 2993-3003.</mixed-citation><mixed-citation xml:lang="en">Ishimaru, C.A. High-affinity iron uptake systems present in Erwinia carotovora subsp. carotovora include the hydroxamate siderophore aerobactin / C.A. Ishimaru, J.E. Loper // Journal of bacteriology. -1992. -T. 174, № 9. -P. 2993-3003.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Laganа, P. First insights from bacteria associated to a polystyrene piece from King George Island (Antarctica) / Р. Laganа, G.</mixed-citation><mixed-citation xml:lang="en">Laganа, P. First insights from bacteria associated to a polystyrene piece from King George Island (Antarctica) / Р. Laganа, G.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Caruso, I. Corsi et al. // International Journal of Hygiene and Environmental Health. -2019. -vol.222, № 1. -Р. 89-100.</mixed-citation><mixed-citation xml:lang="en">Caruso, I. Corsi et al. // International Journal of Hygiene and Environmental Health. -2019. -vol.222, № 1. -Р. 89-100.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Lesic, B. A natural system of chromosome transfers in Yersinia pseudotuberculosis / B. Lesic, M. Zouine, M. Ducos-Galand //PLoS genetics. -2012. -Vol.8,№ 3. Doi: 10/1128/mBio.01875-14.</mixed-citation><mixed-citation xml:lang="en">Lesic, B. A natural system of chromosome transfers in Yersinia pseudotuberculosis / B. Lesic, M. Zouine, M. Ducos-Galand //PLoS genetics. -2012. -Vol.8,№ 3. Doi: 10/1128/mBio.01875-14.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Merhej, V. Yersinia massiliensis sp. nov., isolated from fresh water // V. Merhej // Int. J. Syst. Evol. Microbiol. -2008. -Vol.</mixed-citation><mixed-citation xml:lang="en">Merhej, V. Yersinia massiliensis sp. nov., isolated from fresh water // V. Merhej // Int. J. Syst. Evol. Microbiol. -2008. -Vol.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Orozova, P. Diagnostics and antibiotic resistance of Yersinia ruckeri strains isolated from trout fish farms in Bulgaria / P.</mixed-citation><mixed-citation xml:lang="en">Orozova, P. Diagnostics and antibiotic resistance of Yersinia ruckeri strains isolated from trout fish farms in Bulgaria / P.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Orozova, P.V. Chikova. I. Sirakov // International Journal of Development Research. -2015. -Vol. 5, № 1. -P. 3013-3019.</mixed-citation><mixed-citation xml:lang="en">Orozova, P.V. Chikova. I. Sirakov // International Journal of Development Research. -2015. -Vol. 5, № 1. -P. 3013-3019.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Petrova, M. Tn5045, a novel integron-containing antibiotic and chromate resistance transposon isolated from a permafrost bacterium / M. Petrova, Z. Gorlenko, S. Mindlin // Research in microbiology. -2011. -Vol. 163, № 3. -P. 337-345.</mixed-citation><mixed-citation xml:lang="en">Petrova, M. Tn5045, a novel integron-containing antibiotic and chromate resistance transposon isolated from a permafrost bacterium / M. Petrova, Z. Gorlenko, S. Mindlin // Research in microbiology. -2011. -Vol. 163, № 3. -P. 337-345.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Segawa, T. Distribution of antibiotic resistance genes in glacier environments / T. Segawa, N. Takeuchi, A. Rivera // Environmental microbiology reports. -2013. -Vol. 5, № 1. -P. 127-134. Doi: 11.1111/1758-2229.12011.</mixed-citation><mixed-citation xml:lang="en">Segawa, T. Distribution of antibiotic resistance genes in glacier environments / T. Segawa, N. Takeuchi, A. Rivera // Environmental microbiology reports. -2013. -Vol. 5, № 1. -P. 127-134. Doi: 11.1111/1758-2229.12011.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Spraguet, L.D. Yersinia similis sp. nov. / L.D. Spraguet // Int. J. of Syst. and Evol. Microb. -2008. -Vol. 58. -Р. 952-958.</mixed-citation><mixed-citation xml:lang="en">Spraguet, L.D. Yersinia similis sp. nov. / L.D. Spraguet // Int. J. of Syst. and Evol. Microb. -2008. -Vol. 58. -Р. 952-958.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Ushida, K. Application of real-timePCR array to the multiple detection of antibiotic resistant genes in glacier ice samples / K.</mixed-citation><mixed-citation xml:lang="en">Ushida, K. Application of real-timePCR array to the multiple detection of antibiotic resistant genes in glacier ice samples / K.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Ushida, T. Segawa, S. Kohshima // The Journal of general and applied microbiology. -2010. -Vol. 56, № 1. -P. 43-52. Doi: 10.2323/jgam. 56.43.</mixed-citation><mixed-citation xml:lang="en">Ushida, T. Segawa, S. Kohshima // The Journal of general and applied microbiology. -2010. -Vol. 56, № 1. -P. 43-52. Doi: 10.2323/jgam. 56.43.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
